iFR co-registration

iFR Co-registration

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    Only Philips co-registers iFR values1,2,3 directly onto the angiogram, allowing you to see precisely which parts of a vessel are causing ischemia.

    Advance from PCI justification to physiologic guidance

    iFR Co-registration overview


    With iFR Co-registration there is no need for hyperemic drugs, no need for time consuming pullback devices and no need for guesswork.


    • Mapping of physiologic drops onto the angiogram to better discern focal, serial or diffuse disease
    • Precise lesion severity, location and length assessment
    • Make length measurements without a cumbersome pull back device
    • Physiologic impact of a virtual stent
    • Plan your procedure with physiologic guidance

    Understand lesion-specific physiology


    iFR Co-registration graphically displays the iFR drop along the angiogram, highlighting which portion of the vessel is ischemic.

    ifr coreg focal disease
    Focal disease
    ifr coreg difuse disease
    Diffuse disease

    Make length measurements without a cumbersome pull back device


    iFR Co-registration is calibrated for distance, so with a simple manual pullback you can make measurements on the angiogram and trend line.

    ifr co reg click and drag
    “Click and drag” length measurements help with procedural planning 

    iFR and IVUS tri-registration


    After placing a stent in the mid-vessel, the physician is deciding if they needs to treat the proximal LAD. Tri-registration shows an iFR value of 0.98 and a cross section of 7.9 mm2 by IVUS. The physician decides this intervention is complete.

    v4.0 iFR Tri reg iFR pair
    v4.0 iFR Tri reg no length

    Easy workflow

    Case example: iFR Co-registration workflow

    v4.0 iFR co reg workflow still image

    Related products


    Over 4000 patients have been studied with iFR and numerous prospective iFR studies have been published in peer-reviewed journals.

    iFR Swedeheart

    The two prospective, randomized, controlled trials, with more than 4500 patients' global  physiology studies are Published in The New England Journal of Medicine.

    iFR infographic 2019

    Clinical articles

    State of the art in coronary physiology

    Allen Jeremias video
    Interview with Allen Jeremias, MD4
    Results from this case study are not predictive of future results.


    1. Davies JE, et al., DEFINE-FLAIR: A Multi- Centre, Prospective, International, Randomized, Blinded Comparison of Clinical Outcomes and Cost Efficiencies of iFR and FFR Decision-Making for Physiological Guided Coronary Revascularization. N Engl J Med, epub March 18, 2017.
    2. Gotberg M, et al., Instantaneous Wave-Free Ratio Versus Fractional Flow Reserve Guided Intervention (IFR-SWEDEHEART): A Multicenter, Prospective, Registry-Based Randomized Clinical Trial. N Engl J Med, epub March 18, 2017.
    3. Escaned J. ADVISE II: A Prospective, Registry Evaluation of iFR vs. FFR. TCT 2013. Lecture conducted from San Francisco, CA.
    4. Interview with Allen Jeremias, MD. TCT TV & Videos. 2016